Phospho-Artemis (S516) Polyclonal Antibody, 100ul Insect Expression as is common for collagen

as is common for collagen genes

Elongation factor that can increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA

This locus has experienced positive selection in non-African populations

The C-terminal portion of this protein is proline-rich and contains a conserved region

Mutations in this gene cause dyskeratosis congenita (DKC)

Phospho-Artemis (S516) Polyclonal Antibody, 100ul Insect Expression as is common for collagenDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative