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These effects are typically dose-dependent and can be minimized with proper guidance

J Orthop Res 24:11091117 Staresinic M, Sebecic B, Patrlj L, Jadrijevic S, Suknaic S, Perovic D, Aralica G, Zarkovic N, Borovic S, Srdjak M (2003) Gastric pentadecapeptide BPC 157 accelerates healing of transected rat Achilles tendon and in vitro stimulates tendocytes growth

Surface coating with cyclic RGD peptides stimulates osteoblast adhesion and proliferation as well as bone formation

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